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ISSN 2063-5346
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Evaluation of wound healing and anti-inflammatory potential of Daucus Carota ethanolic Extract in laboratory animals

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Padmaja Kore, Mansi Sewatkar, Vaishnavi Inde, Abhishek Nemmaniwar , Anuradha More, Minal Harde, Sakshi Khandagale, Tanvi Mande, Shivani Harne, Neha Dhumal, Pooja Chavan
» doi: 10.31838/ecb/2023.12.sa1.221

Abstract

Wild carrot, also known as Queen Anne's Lace, was introduced to North America from Europe as a medicinal herb., Daucus Carota is sanctified with a wide variety of qualities which are mainly indicated in Ayurveda to be used for Mehahara (treats urinary tract disorders), Deepana (enhances stomach fire), Pachana (helps in digestion), Rochana (stimulates appetite) The ethanol extract of the leaves of D. Carota (DCEE) was investigated for its healing efficiency in a rat excision wound model. Methods: We divided the three groups of eight rats into excision wounds. The rate of wound contraction in skin wound sites in rats treated with 10% (w/w) betadine ointment or the reference standard medication, 5%, 10%, or 15% (w/w) DCEE ointment, was used to measure healing. Estimates were made of how DCEE affected the amounts of hydroxyproline and hexosamine during the healing process. Also evaluated was DCEE's antibacterial efficacy towards microbes. To comprehend the mechanism of wound healing, the in vivo antiinflammatory activity of DCEE was examined.

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