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ISSN 2063-5346
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“EMERGING ROLE OF DIETARY POLYPHENOLS AND HERBS IN PARKINSON’S DISEASE”

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Maruti Shelar, Aarti Ombase
» doi: 10.31838/ecb/2023.12.sa1.010

Abstract

Parkinson's disease (PD) is a slow-progressing neurodegenerative disease characterised by dopaminergic neuron loss in the nigrostriatal pathway. Despite decades of research, disease therapeutic options are severely limited, providing just symptomatic relief and failing to prevent progression of the disease. Moreover, the average drug treatment expenses and therapeutic surgical procedures are highly expensive. Besides that, the overall number of Parkinson's disease patients worldwide is increasing dramatically, which has a significant impact on individual and social lives of patients. As a result, herbal supplements for treating and preventing Parkinson's disease have received a lot of attention in past few decades. Herbal remedies, phytochemicals, and polyphenolic compounds derived from food supplements, fruits, vegetables, and spices can help to prevent, delay, or alleviate the symptoms of long-term neurological disorders, and also improve cognition, learning, and overall brain health and welfare. Innumerable plants and polyphenolic compounds have been recognised in recent scientific studies as having healing properties against neurological diseases including such Parkinson's disease and Alzheimer's disease. As a result, the aim of the review is to describe some of the most medicinally significant herbal supplements and polyphenols in terms of their neuroprotective potential, as well as to aid in the discovery of possible therapeutic interventions for Parkinson's disease

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