Under the perception of medication, medication reconciliation is an instrumental process in medical settings to save the precision and safety of patients' drugs. Pharmacy assistants seriously contribute to the process of medication reconciliation, though the level of their participation and the range of functions performed may differ among hospitals. This piece delves into the critical analysis of pharmacy assistants' role in the medication reconciliation process. Furthermore, the responsibilities, difficulties, and role in patient care delivery will be examined. Through a literature review involving some case studies, this study drew up an analysis that demonstrates the usefulness of pharmacy technicians in the medication reconciliation process as well as the limitations that need to be accommodated. The approach to channeling pharmacy assistants' role in medication reconciliation procedures is also highlighted, and staff safety, as well as health outcomes, are considered in this regard.