We shall begin this chapter by discussing the current state of pharmacy practice research and its potential future directions. The background is then established by a discussion of major concepts from the research approach used in this chapter. This includes, but is not limited to, changes in demographics, advances in medicine, the pharmacy's institutional role, and customer preferences. Alterations in the pharmaceutical market and customer behavior are two further instances. In addition, it highlights the significant development in pharmacy research throughout the previous several decades. The capacity to define and evaluate the effects of pharmaceuticals, the diversity of patient cultures, and the interprofessional collaboration and partnership with patients are all examples of developments that fall within this category. In the article's last paragraph, the authors focus on the methods that will likely be employed in future research on pharmacy practice. It is becoming more usual to work with large and complicated data sets; conducting research using electronic health records has unique methodological challenges; and academics studying pharmacy practice use a diverse range of methodologies that supplement one another.