Urea, sodium salicylate, sodium citrate, sodium acetate, sodium benzoate and nicotinamide. concentrated aqueous hydrotopic solution have been seen to increase the aqueous solubility of numerous medication that aren’t vary water-soluble. In order to improve the first solute’s solubility in water, a second solute must be added in high quantities, which eliminates the need for organic solvents. These hydrotropes are inexpensive and non-polluting. In the current study, Rosuvastatin, a poorly-water soluble medication, was hydrotropically solubilized for spectrophotometric analysis using 1M sodium benzoate. At 244nm, rosuvastatin demonstrates maximal absorption. Beer’s law was discovered to be upheld for concentration. There is no interference from conventional pharmaceutical additives or diluents in this approach. RSV correlation coefficient was (or “r” value) 0.9994. the analysis finding have been confirmed in accordance with ICH criteria, with Rosuvastatin calcium, the percentage recovery ranges from 99.97 to 99.98%. The procedure is accurate, exact and cost-effective.