For effective teaching learning process and to cover the divergent need and aspiration of the Nursing students a number of strategies are adopted by the teachers. Among them E-learning and Face to Face learning are the two strategies which are very relevant in the present changing situation. Hence it is a very burning current research area. This study aims to investigate use of E-learning and Face to Face learning strategies for Nursing students in relation to their parental educational variation, occupation and income . Convenient sampling method was used to select 300 nursing students studying in different nursing colleges of Kolkata. A 5 point likert scale questionnaire was used. Result shows that obtained “t” value 0.92 < the tabular value at 0.05 levels so there exist no significant difference between the use of E-learning of nursing students in relation to parental educationvariation whereas there exist significant difference between the face-to-face learning of nursing students in relation to parental educationvariation as the obtained “t” value 2.92 > the tabular value at 0.05 levels so . There exist significant difference betweenthe use of E-learning and face to face learning of nursing students in relation to parental occupationvariation as the obtained “t” value 3.00 & 2.99 respectively > the tabular value at 0.05 level . There exist significant difference betweenthe use of E-learningand face to face learning of nursing students in relation to parental incomevariationas the obtained “t” value 3.82 & 3.18 respectively > the tabular value at 0.05 level . It is concluded that parental education have no relation with E-learning of nursing students but parental occupation and income have significance relation with E-learning and Face to Face learning strategies for Nursing students.