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ISSN 2063-5346
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TO EVALUATE THE EFFICACY OF FIVE MOUTHWASHES IN REDUCING VIRAL LOAD/BACTERIAL COLONIES IN ORAL CAVITY

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Dr. Rahul paul, Dr. Deepti Yadav, Dr. Vineet Golchha, Dr. Mudita Gupta, Dr. Vandana Gulia Dr. Ekta Sharma
» doi: 10.31838/ecb/2023.12.sa1.249

Abstract

Human viral infection and transmission can occur through multiple paths, such as fecal–oral, exchange of saliva or by aerosols generated by sneezing or coughing Influenza and the common cold viruses(Rhinovirus) are among the most frequent types of human viral infections. This study is conducted to study efficacy of five mouthwashes in reducing viral load/bacterial colonies in oral cavity The Aim of this study is to evaluate the efficacy of 5 different mouthwashes for reducing viral load and bacterial colonies in oral cavity The study was initiated with 75 patients who were divided into five groups randomly and every group was assigned 15 patients and one mouthwash and 4 samples were taken for every patient . First two samples on first visit and 3rd , 4th sample on second visit. Patients were asked to collect 1st saliva sample using Eppendrof tubes then patient rinsed their mouth using the assigned mouthwash and second sample was collected after 2 hours of rinsing with mouthwash. Sample was stored at -80 degree. Interleukin 6 levels were tested using Elisa kit for Rhinovirus and colony forming unit on blood agar medium was used for streptococcus.Hydrogen peroxide followed by chlorhexidine and triclosan showed significant reduction in bacterial colonies with highest mean difference followed by hydrogen peroxide. Hydrogen peroxide showed maximum reduction in viral load followed by chlorhexidine hence proving their efficient

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