Tinospora cardifolia which is commonly known as Giloy or Guduchi and grows in the form of a shrub has a wonderful role in ayurvedic drugs. In the modern medicine, number of chemicals have been isolated from different part of Tinospora cardifolia and were found very effective in the management of major ailments. On one hand Tinospora cardifolia has a very potential role as anti-diabetic drug and is also helpful in arthritis and malaria. A good number of researchers have found that Tinospora cardifolia is very effective as anti-cancer drug. Tinospora cardifolia is also used as immunomodulator and enhance the general health of individual. In the latest epidemic of COVID-19, researchs have proved that use of Tinospora cardifolia has helped a lot in early recovery. It is reported that with ayurveda intervention having Tinospora cardifolia, have accelerated the recovery in terms of symptoms and duration of hospital stay.