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ISSN 2063-5346
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THERMOPHILIC CYANOBACTERIA: AN UNTAPPED RESERVOIR OF PHARMACOLOGICAL LEADS

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Sachin Tyagi1 , Sarvesh Suyal2 , Anurag Tewari3 , Sadhna Awasthi4 , Rahul Kunwar Singh5 , Ashok Kumar6 , Navneet Sharma6 and Akshat Uniyal7*
» doi: 10.53555/ecb/2023.12.si5a.0161

Abstract

The pharmacological leads are the characterized bioactive and natural compounds. This could be achieved by the various approaches such as conventional and combinatorial genomic methods. The developments of pharmacological leads are the first steps, which identified the possible targets against the microbial agents. However, the current pace of leads search doesn’t meet the requirements of drug discovery programs due to emergence of drug resistance and new microbial pathogens. Cyanobacteria considered the microbial fossils of the first photosynthetic organisms along with the longest evolutionary history on earth. Cyanobacteria reported and documented the varieties of natural compounds with the diverse chemical profile. However, thermophilic cyanobacterial origin compounds have been studied very least for this purpose, and considered the huge, hindered repository for the varieties of pharmacological leads. Therefore, present communication explored the untapped thermophilic cyanobacteria for the possible pharmacological leads.

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