Background: Pharmacists play a crucial role as accessible and trustworthy healthcare professionals, particularly in community settings. The importance of clinical pharmacists in ensuring safe medication use has been increasingly recognized. However, the COVID-19 pandemic has significantly impacted pharmacists' roles and health status, leading to challenges such as increased infection risks, work disruptions, and mental health issues. Objective: This research aims to assess the impact of pharmaceutical care interventions on managing and preventing COVID-19 in the community, evaluate the effectiveness of pharmaceutical care services in improving public health outcomes during the pandemic, investigate pharmacists' role in promoting public health education related to COVID-19, and identify barriers and facilitators to implementing pharmaceutical care services in public health settings during the crisis. Conclusion: Despite facing various challenges during the pandemic, pharmacists have demonstrated resilience and adaptability in providing essential pharmaceutical care services. They have played a critical role in managing and preventing COVID-19, promoting public health education, and collaborating effectively with medical teams. Through remote patient interactions and creative solutions in hospitals, pharmacists have ensured the safe and effective use of medications, contributing significantly to safeguarding public health and enhancing patient outcomes during these unprecedented times. Recognizing and supporting the invaluable contributions of pharmacists is crucial for navigating through the ongoing global health crisis effectively.