Infection control refers to the policies and procedures designed to control and minimize the spread of infection in hospitals and other healthcare facilities, with the primary purpose of reducing infection rates. Infection control was introduced to the United States as a formal entity in the early 1950s. In the late 1950s and 1960s, a small number of hospitals began to recognize healthcare-associated infections (HAIs) and implement some infection control concepts. This activity examines the types of infection control methods and their indications and highlights the role of the interprofessional team in adhering to infection control principles to improve outcomes. The purpose of this article is to identify the most effective and cost-effective ways for providers to prevent the spread of infection, summarize standard precautions, contact precautions, droplet precautions, and airborne precautions, and review what is needed for patients with Types of preventive measures: A patient with tuberculosis is a patient with Clostridium difficile and an interprofessional team strategy is outlined to ensure appropriate infection control measures are in place to prevent the spread of infection in the healthcare setting.