The hierarchical structure that traditionally exists between these two professions can significantly impact communication, collaboration, and overall patient care outcomes. By examining existing literature and studies on this topic, this review aims to shed light on the various factors that contribute to power differentials and their effects on the working relationship between nurses and doctors. The review begins by discussing the historical context of the nurse-doctor relationship and how power differentials have been perpetuated over time. It then delves into the various sources of power within healthcare settings, including institutional, professional, and personal sources of power. These power dynamics can manifest in subtle ways, such as through communication patterns, decision-making processes, and the distribution of responsibilities. Furthermore, the review explores the impact of power differentials on collaboration and teamwork between nurses and doctors. Research has shown that when power imbalances are present, it can lead to conflicts, misunderstandings, and a lack of respect between the two professions. These issues can ultimately compromise patient care and safety. In addition, the review examines strategies and interventions that have been proposed to address power differentials and improve the nurse-doctor relationship. These include interprofessional education, communication training, and fostering a culture of mutual respect and collaboration within healthcare teams. By implementing these strategies, healthcare organizations can create a more equitable and effective working environment for both nurses and doctors. Overall, this review highlights the importance of recognizing and addressing power dynamics in the nurse-doctor relationship. By promoting a more balanced distribution of power and fostering open communication and collaboration, healthcare teams can work together more effectively to provide high-quality care to patients.