The present study deals with the GC MS analysis of one Ayurvedicmedicine, Guggulu Panchapalam Churnam which is a digestive formulation. The medicine was procured form standard Ayurvedic vendor at Chennai and was subjected to GC MS analysis after proper processing. As many as 57 compounds were shown in the GC MS profile. Some of the molecules such as Cinnamaldehyde, (E)-, Benzoic acid, 4-isopropyl-, ethyl ester, Undecanoic acid, 10-methyl-, methyl ester, Caryophyllene oxide, Tridecanoic acid, 12-methyl-, methyl ester, 1-Heptatriacotanol, .beta.-Sitosterol, 5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one, 1,1a-.alpha.,1b-.beta.,4,4a,7a-.alpha.,7b,8,9,9a-decahydro-4a-.beta.,7b-.alpha.,9a-.alpha.-trihydroxy-3-(hydroxymethyl)-1,1,6,8-.alpha.-tetramethyl-, 9a-isobutyrate, trans(2-Chlorovinyl)triethylsilane indicated many medicinal roles which correspond to that of GugguluPanchapalamChurnam. The medicinal roles of some compounds are not known and warrant further research on them. It is concluded form the above results and discussion that,the role of GugguluPanchapalamChurnam as digestive medicine augurs well with the roles of the molecules present in it.