This study aimed to evaluate the effectiveness of vaccination campaigns in preventing the spread of communicable diseases through a systematic review of existing literature. The analysis focused on the impact of vaccination campaigns on disease transmission rates and overall public health outcomes, revealing that vaccination campaigns are highly effective in reducing the incidence of communicable diseases and controlling outbreaks. The study emphasized the importance of high vaccination coverage rates in achieving herd immunity and protecting vulnerable populations. The findings underscore the crucial role that vaccination campaigns play in preventing the spread of communicable diseases and promoting public health.