The purpose of this review article was to assess whether “Type 2 Diabetes Mellitus Patients' (T2DM)” “Atherogenic index of plasma (AIP)” could serve as a predictor for “Coronary Artery Disease (CAD)”. A significant complication of T2DM that has a high risk of morbidity and mortality is CAD. AIP has been suggested as a helpful indicator of CAD risk. It is calculated as the logarithm of the ratio of triglycerides to high-density lipoprotein cholesterol. Many researches have looked into the connection between AIP and CAD in T2DM patients, and the findings have consistently shown that this population has a much higher risk of developing CAD when AIP levels are higher. Nonetheless, there is still debate about the use of AIP as a clinical biomarker for CAD risk in T2DM patients, and more research is required to confirm its usefulness in clinical practice. Furthermore explored is the potential of AIP as a therapeutic target for the prevention and treatment of CAD in people with type 2 diabetes.