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ISSN 2063-5346
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TERIPARATIDE FOR TREATMENT OF PATIENTS WITH BISPHOSPHONATEASSOCIATED ATYPICAL FRACTURE OF THE FEMUR

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Dr Sushant Kumar (Resident), Dr Anteshwar Birajdar (Associate Professor), Dr Mukesh Phalak (Professor and Head), Dr Sarthak Walia (Resident), Dr Archit Gupta (Resident)
» doi: 10.31838/ecb/2023.12.s2.236

Abstract

Introduction: Antiresorptive drugs such as bisphosphonates are widely used for the treatment of osteoporosis. Although effective for prevention of osteoporotic fractures, use of bisphosphonates is associated with rare but serious adverse events such as osteonecrosis of the jaw and atypical femur fractures (AFFs). Methods: Patients who had been diagnosed with an atypical subtrochanteric and femoral fracture linked to the use of bisphosphonates were analysed. All underwent surgical intervention and teriparatide usage was suggested after surgery. Perioperative results, clinical And Radiographic Outcomes Were Considered Outcome Indicators. Results: A total of 16 patients were included in the study. Depending on whether they had teriparatide medication or not they were divided into two groups. In the teriparatide treated group the mean time to bone union was 4.1 months and modified HHS at 6 months was 80.4 Conclusion: Post surgical management of AFF with teriparatide improves the fracture healing and improves the pain in patients with impaired bone turnover.

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