Malignant neoplasm, another name for cancer, is a horrible condition that can invade or spread to other sections of the body due to aberrant cell proliferation. According to the World Health Organization's 2015 study, cancer causes 8.8 million deaths globally, or one in every six fatalities, with 70 percent of those deaths occurring in low- and middle-income nations. Despite the fact that there are several anticancer drugs available nowadays, certain big cancer forms are incredibly resistant to them. Due to their considerable pharmacological activity, as was already noted, benzimidazole and thiazoles are important pharmacophore in medicinal chemistry. We selected these two for our analysis because of their capacity to combat cancer. In order to construct a possible anticancer agent, certain benzimidazole derivatives were made. Here is a representation of the synthesised derivaties' model skeleton.