The article describes a method for obtaining new bis-amides synthesized by the amidation reaction of 1,1-bis- (carboxymethyl)-1-arylethanes with some primary amines. Their physico-chemical characteristics are determined. The structure of the synthesized compounds is confirmed by the data of elemental analysis, IR and NMR (1H and 13C) spectra. It was found that with the ratio bis-acid:amine equal to 1:2 the yield of the corresponding amides is 56.0-96.0%. The fungicidal and bactericidal properties of the synthesized compounds were investigated. General analysis of antibacterial and antifungal activity showed that the synthesized compounds are active against Fusarium oxysporum and Klebsiella pneumoniae. Pyridine-2-amide of 1,1-bis-(carboxymethylthio)-1-phenylethane had the highest fungicidal and bactericidal activity among all studied amides introduced in 0.1% concentration into both dry and solid nutrient media.