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ISSN 2063-5346
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SYNTHESIS AND CHARACTERIZATION OF SOME HETEROCYCLIC COMPOUNDS (AZETIDINE, OXAZEPINE) DERIVED FROM SCHIFF BASES AND EVALUATION OF THEIR BIOLOGICAL ACTIVITY.

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Nadia Sadiq Majeed, Zainab Hassan Rahim
» doi: 10.31838/ecb/2023.12.s3.441

Abstract

In this study, Some new Compounds have been Synthesized including the preparation of some Schiff bases form the reaction terphthadehyde compound with two moles of aniline derivatives (2-amino-5-methyl benzoic acid ,3-amino phenol) ,also. The stage include preparation of new heterocyclic compounds four-membered (β-Lactam) using the traditional methods and seven membered ( Oxazepine, Oxazepane) using the microwave methods. The prepared compounds were characterized by FT-IR spectra, 1H-NMR, and 13C-NMR spectra, in addition to their melting points and TLC (Thin Layer Chromatography).finally the prepared compounds are tested against Gram-positive and Gram-negative bacteria to study their biological activity

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