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ISSN 2063-5346
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SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NOVEL FLAVANONE INCORPORATED SEMICARBAZIDES

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Tripti Verma, Chandra Shekhar Sharma
» doi: 10.31838/ecb/2023.12.si5.019

Abstract

A series of novel flavone incorporated semicarbazides (5a-5g) was synthesized and characterized by elemental analyses, 1H NMR, and mass spectral studies. The newly synthesized compounds were screened for their anticonvulsant activity against Pentylenetetrazole (PTZ)-induced Convulsions model in male wistar rats and compared with the standard drug phenytoin. Compound 5e was found to be most active compound as comparable to standard drug phenytoin

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