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ISSN 2063-5346
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Synthesis and anti-depressant activity of JC-41 and JC-42 in Interferon-alpha (IFN-α) induced depressant-like behaviour in mice

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Amit Kumar Sharma1 , Tanveer Naved1*, Vikramdeep Monga2* , Rajnish Kumar Malik1
» doi: 10.48047/ecb/2023.12.1.557

Abstract

Interferon-alpha (IFN-α) is a useful therapy for some types of cancers and viral infections. Chronic use of IFN-α is related to psychological symptoms such as depression. The present study was designed to test the anti-depressant effects of two synthesized hydrazide derivatives, JC-41 and JC-42 in an IFN-α induced depression in the mice model. Female Swiss mice (25– 30g) were used

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