Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Background: Health care associated sepsis in children is a global health problem. Predisposing to this infection may include single nucleotide polymorphism (SNP) in interleukin 1 β gene (IL1 β). Objective: the aim was to study the association of L-1β +3954 C>T polymorphism in children with health care-associated sepsis. Method: The study is a retrograde case-control study that included ninety two children with hospital-acquired sepsis and ninety two children as control group. Blood samples from included children were subjected to blood culture for identification of sepsis and SNP study of IL1 β by polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP).