.

ISSN 2063-5346
For urgent queries please contact : +918130348310

Study of Serum Pepsinogen 1 And Pesinogen1 to Pepsinogen 2 Ratio Level as A Screening for Atrophic Gastritis and Gastric Cancer

Main Article Content

Mohamed SalahEldinMetwaly Abozamel1, ,Aymen Mohamed Shamsya1, Wafaa Mohamed Hesien1, Mona Wagdy Ayad2, Amany Ahmed Elbanna1
» doi: : 10.48047/ecb/2023.12.5.174

Abstract

Objective:To evaluate pepsinogen1 (Pg 1) level in serum and pepsinogen1 to pepsinogen2 ration (Pg 1/2) in patients with AG and GC and compare them to gold standard endoscopic examination in those patients, to detect the sensitivity and specify of these markers to evaluate their value as a future seromarker or tumor marker. Patients and Method: This was an observational case-control comparative study that included 60 patients diagnosed with atrophic gastritis and gastric carcinoma. A clinical and endoscopic examination were used to make the diagnosis, and gastric biopsies were examined histologically to confirm it.Two separate groups of patients were formed, with 30 patients involved within group 1 having AG and 30 patients in group 2 having GC. As a control group, 30 healthy volunteers were enlisted. Informed written consent will be taken from all patients.

Article Details