Aims & Objective: To study and correlate the clinical symptoms with spirometry abnormalities in COPD patients. Methodology: This study was carried out in 175 patients who presented with symptoms of COPD. In all patients PFT, CHEST X-RAY, ECG, 2D-Echo were done. Additional investigations required for further diagnosis and management were also done. Results: Out of 175 patients of COPD, mean age of patient was 58.73 ± 8.68 years with male preponderance of 5.73:1. Mean FEV1 was 45.32 ± 12.56% of predicted, range 17 to 77 % of predicted. Maximum number of patients (52%) had severe airflow obstruction at the time of presentation and only (10.28%) had very severe airflow obstruction. Mean FEV1/FVC% was 49.67 ± 12.51% of predicted, range 22 to 70 % of predicted. The majority cases 26.28% had FEV1/FVC ratio in < 40% followed by 25.71% had FEV1/FVC between 41- 50%. Marked ECG changes are there with severity of the disease stage having prevalence of 65.71% with P pulmonale. The prevelance of 2D ECHO findings increases with the severity of the disease stage with findings of PAH 53.19% patients. Conclusion: Computerized spirometry is very much a useful investigation in the management of chronic obstructive pulmonary disease. FEV1 values can be used as diagnostic, as well as to assess the severity of the disease. Now that in upcoming era HRCT is also being used for grading the severity of the disease.