The supply of common necessities has significantly increased as a result of recent population growth. Mineral processing offers numerous opportunities to enhance environmental and energy performance. The majority of industrial operations require some kind of reduction in size. It is now accepted that the size of the fineness achieved by a particular grinding method accounts for more than half of the total cost. This is true in any mineral beneficiation plant, regardless of the method used to enrich the total separation of one or more valuable species from natural ore. Limestone ore was used in this study for ball mill grinding tests. Five feed (ore) sizes and three ball sizes were used in the experiments. The upsides of selectivity capability for three arrangement of feed sizes with three different ball sizes have been assessed. Process optimization was also employed and analyzed for ANOVA and Regression analysis.