The development of the technology, science and economy has great influence in linguistic sphere. Nowadays, business terminology and its analysis from different angles of linguistics have not been studied so thoroughly. In this article, the lexical units of business sphere in English and Uzbek languages are investigated and compared. It should be stated that in English language, business terminology is mostly formed with the help of affixation, in particular, with the help of prefixes, suffixes, circumfixes. Besides, among English business terminology, the samples of compounding and idioms were also noticed in many cases. In Uzbek language, business terminology can be divided into archaic and modern types, and it must be mentioned that mostly new business terminology is based on neologisms.