Sweating is a biological mechanism that helps to synchronize temperature of human body. Foot odor is produced by metabolism of gram-positive bacteria such as Staphylococcus epidermis, Bacillus subtilis and Propionibacterium Acnes. Microbial vegetation present over foot-skin causes break-down of protein as well as lipid containing secretion of exocrine glands. Enzymes responsible for break-down of lipids and proteins are proteases and lipases. It disrupts the protein and lipids into free fatty acids (short-chain) and amino-acids. These are eventually vaporized in atmosphere owing to its type of chemical. Further, such compounds which are volatile in nature finally move to receptors of nose and are noticed as unlikable odorants. Few spray products containing natural oil/s are available. However, these products have stability issue due to phase separation, and it produce stain on foot skin or apparel.The present study focussed on solubilizing the essential oil/s and tested susceptibility of Bacillus subtilis and Staphylococcus epidermidis to oil combinations. The outcome showed that a combination of lemon oil, neem oil and tulsi oil possessed synergistic antibacterial activity. A foot deodorizing liquid roll-on was prepared using different solubilizers and tested. The liquid roll-on preparation showed desired properties such as stability, clarity, consistency, spreadability, quick absorption post application, non-stickiness and non-dryness, and absence of residue. The foot preparation demonstrated antibacterial efficiency against the bacteria responsible for producing a strong foot odour.