The purpose of the current work was to create a solid dosage form tablet of self-micro emulsifying drug delivery system (SMEDDS) by adsorption liquid self-micro emulsifying drug delivery system with an inert solid carrier aerosil 200 and avicel PH 102 to increase the oral bioavailability of the medication Simvastatin, which is poorly water-soluble. Simvastatin, capryol 90, tween 80, and polyethylene glycol 400 were the ingredients of the self-micro emulsifying drug delivery system. The self-micro emulsifying drug delivery system examination revealed that the particle size was in the micro emulsion region. Magnesium stearate, polyvinylpyrrolidone, and avicel PH 102 were used in the direct compression method to turn the solid self-microemulsifying drug delivery system into a tablet. Tablets, self-micro emulsifying drug delivery systems, solid self-micro emulsifying drug delivery systems, and plane drug. Simvastatin's release rate was much lower than that of self-micro emulsifying drug delivery systems, solid self-micro emulsifying drug delivery systems, and tablet formulations. The findings of this study suggested that prepared tablets might be utilised as an efficient oral solid dosage form to increase the solubility and bioavailability of Simvastatin, a medication that is poorly soluble in water.