Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Objective: To develop and validate a simple, efficient and cost-effective stability indicating RP-HPLC method for simultaneous estimation of Clonidine and Hydrochlorothiazide in Tablet dosage form. Methods: Phosphate buffer (ph6.0)-Methanol and Triethylamine (70:30:0.1) used as mobile phase and stationary phase (250*4.6mm C18, Hypersil BDS) column, wavelength was selected 226 nm, Flow rate 1.0 ml/ min, injection volume 20 µl and column oven temperature 25°C. Prepared Standard solution and sample solution at working concentration, used Mobile phase as diluent