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ISSN 2063-5346
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SILICA-SUPPORTED 2,4,6-TRICHLORO-1,3,5-TRIAZINE (SILICA-TCT): ENVIRONMENTALLY BENIGN, MILD AND EFFICIENT CATALYST FOR THE SYNTHESIS OF 1,4-DIHYDROPYRIDINES UNDER SOLVENT-FREE CONDITIONS

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Rajesh H. Talea , Ramprasad U. Siraskara and Sainath B. Zangade
» doi: 10.17628/ECB.2013.2.279

Abstract

A convenient and environmentally benign silica-supported 2,4,6-trichloro-1,3,5-triazine (Silica-TCT) catalyzed Hantzsch multicomponent reaction has been shown between aldehydes, 1,3-dicarbonyl compounds and ammonium acetate in combination with stirring at room temperature under solvent-free condition to yield 1,4-dihydropyridines. Use of Silica-TCT catalyst gives several advantages in terms of simple reaction procedure, no need of organic solvent, mild reaction conditions giving quantitative yield of desired product

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