Health screenings play a crucial role in the early detection of diseases, allowing for timely interventions and improved health outcomes. This study explores the essential roles of nurses and laboratory professionals in health screenings for early disease detection. Nurses are at the forefront of patient care, conducting screenings, collecting samples, and providing education on preventive measures. Laboratory professionals play a vital role in analyzing samples, identifying biomarkers, and generating accurate test results. Together, they form a collaborative team that ensures the effectiveness and efficiency of health screenings. This study examines the responsibilities, challenges, and impact of nurses and laboratory professionals in health screenings, highlighting the importance of their roles in promoting public health and disease prevention.