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ISSN 2063-5346
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REVIEW ON GASTRO RETENTIVE DRUG DELIVERY SYSTEM: TREATMENT OF HELICOBACTER PYLORI INFECTIONS

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Aarati Maurya, N. G. Raghavendra Rao, Anuj Pathak, Balwan Singh, Irfan Ali
» doi: 10.31838/ecb/2023.12. 4.093

Abstract

The recent technological investigations have been devoted towards different oral controlled release formulations. Floating formulations have now become the most fascinating and popular dosage forms in the present time. They introduced various novel technologies are used to enhance the retention time of the formulation in gastric region, there by achieving a zero order release. The conventional oral drugs are absorbed in the upper region of the Gastro intenstinal part or have a narrow absorption window have poor bioavailability because of shorter residence time. Pharma companies have acquire much attract in pharmaceutical investigations in the area of controlled release formulations most widely on floating formulations. The main goal of present review on GRDDS focusing on its present, future, and treatment of h. Pylori infections. To enhance the bioavailability and the increase the gastric residence time (GRT), controlled release drug delivery system can be used. One such system is the Gastroretentive drug delivery system, which was developed to convey the narrow absorption window drugs with enhanced bioavailability. In this review covers the advantages, disadvantages, ongoing floating techniques, advanced process to increase the floating gastric residence time of formulations, and research advancements made in GRDDS are deliberate

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