COVID-19 is a pathology that affects lung function and its severity can be influenced by the existence of previous pathologies such as cardiovascular, pulmonary and autoimmune diseases. Methods: The present study is cross-sectional and observational. The sample colletion lasted six months and took place at Beira Baixa, Portugal. The sample involved 331 individuals. The variables collected were age, presence of cardiovascular, pulmonary and autoimmune pathologies, as well as COVID-19 infection and associated symptoms. Results: The most prevalent age class was from 30 to 50 years old. The severity classification of COVID-19 was considered asymptomatic in 54 subjects, mild in 226, moderate in 44 and severe in seven participants. The most prevalent pre-existing comorbidity was arterial hypertension. Conclusion: The severity of symptoms triggered by COVID-19 was not influenced by the pre-existence of comorbidities in infected individuals