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ISSN 2063-5346
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RECENT ADVANCEMENT ON VARIOUS POSSIBLE FORMULATIONS OF ARTEETHER AND FUTURE ASPECTS: A COMPREHENSIVE REVIEW

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Pallvi Saroch , Gurpreet Singh , Asif Ramzan , Sameer Raj , Peer waris Ul Haq, Chandrashekhar kumar
» doi: 10.31838/ecb/2023.12.s1-B.212

Abstract

Arteether is a well-known antimalarial drug with high commercial success because of its use in drug resistance cases of malariait is a readily accessible antimalarial medicine that may be given intramuscularly as an oily solution (11.).The injection is painful and patient noncompliance so here we are discussing various possible oral dosage form of arteether. Arteether is used to treat both cerebral malaria and chloroquine resistant malaria. However, the primary issues with arteether are its limited solubility (≅17 μg/ml) and ≅ 40 % gastrointestinal breakdown. So these problems are challenge. Because of these issues, developing an oral dose form with high bioavailability is difficult. According to the literature survey we try to develop some possible oral dosage form of arteether(i.e. Spheroids, liposomes, Nano lipid carriers, self-emulsifying drug delivery system (seddss), colon targeted matrix tablets, Enteric coated tablets).Arteether oral formulations can be optimised for rapid and full medication absorption

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