"Dengue fever" (DF) is a serious public health issue, particularly in South Eastern parts of Asia. Biochemical changes have been proven to be early indicators of DF. This study was done on 90 DF patient to investigate the influence of the disease on liver functions along with lipid profiles and to link the results with the degree of seriousness of the disease. The current cross-sectional and observational study included 90 participants. Frequency and percentage were used to express qualitative data. The experimental investigation comprised a DF test with a quick diagnostic kit, liver function testing, and lipid profile tests. Quantitative data was reported utilizing the "mean standard deviation" as well as "median".