In the fight against COVID-19, healthcare professionals (HCPs) such as physicians, nurses, pharmacists, and laboratory personnel are at the forefront of the struggle. They are also at an elevated risk of becoming infected with the coronavirus. Utilizing the appropriate personal protective equipment (PPE) is one way to reduce the likelihood of contracting an illness. HCPs will be able to use personal protective equipment (PPE) effectively and save unnecessary costs if they have a better understanding of its role. This will also ensure that the nurse-patient relationship continues to be the primary focus of treatment. It is essential for health experts to effectively adopt preventative and control measures in order to bring the dangerous COVID-19 epidemic under control.