A lot of interest has been paid to silver nanoparticles (AgNPs) because of their distinctive physicochemical characteristics and diverse range of uses. However, worries have been voiced about their potential negative health impacts on people. The objective of this review paper is to present a thorough examination of the effects of AgNPs on human health after exposure through a variety of methods, including inhalation, oral ingestion, cutaneous absorption, and injection. We'll talk about how AgNPs affect the reproductive system, neurological system, cardiovascular system, and gastrointestinal tract.