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ISSN 2063-5346
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ORAL TRANSMUCOSAL DRUG DELIVERY OF POLYSACCHARIDE POLYMERIC COMBINATION

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Swapnil Salunkhe, Dr. Shweta Shriwas, Dr. Sourabh Jain, Dr. Rakesh Patel
» doi: 10.53555/ecb/2022.11.10.216

Abstract

Oral route is one of the most preferred routes of drug administration due to its safety, ease of administration, and acceptability by patients. About 60% of conventional dosage forms are available as the oral solid dosage forms. Orally dissolving strips and films are useful in patients such as pediatrics, geriatrics, bedridden, and emetic patients and conditions such as sudden episodes of allergic attacks or coughing. Psychois is a condition characterized by the hallucination, dementia etc. seizures. It requires quick management of in order to avoid the risk of permanent brain damage. Pharmacotherapy with anti-psychotic drugs remains the major treatment modality for psychosis. The formulation of anti-psychotic as an orally dissolving strip, required to be placed on the patient’s tongue without swallowing for dose administration, would significantly facilitate dose administration, with subsequent improvement in patient compliance. Thus, the aim of this work was to design, develop and characterize mouth dissolving film of Anti-psychotic drugs. The backbone of an orally dissolving film is generally formed of a plasticizer and film forming polymer or a mixture of polymers that provide the necessary elasticity and shape to the film.

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