Pressure ulcers are a common and serious complication among patients receiving wound care, particularly those with limited mobility or underlying health conditions. Nursing interventions play a crucial role in preventing the development of pressure ulcers and promoting optimal wound healing. This review article aims to explore the various nursing interventions that have been implemented to prevent pressure ulcers in wound care settings. A comprehensive literature review was conducted to identify relevant studies and evidence-based practices in this area. The review highlights the importance of early risk assessment for pressure ulcers, including the use of standardized tools to identify at-risk patients. Nursing interventions such as regular repositioning, proper wound care techniques, the use of support surfaces, and patient education are essential components of pressure ulcer prevention strategies. Additionally, the role of nutrition, hydration, and skin assessment in maintaining skin integrity and preventing pressure ulcers is discussed. Furthermore, this review examines the impact of technology and innovation in nursing interventions for pressure ulcer prevention, including the use of pressure-relieving devices and telemedicine for remote monitoring of at-risk patients. By implementing evidence-based practices and continuous monitoring of at-risk patients, nurses can play a pivotal role in reducing the incidence of pressure ulcers and improving patient outcomes in wound care settings.