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ISSN 2063-5346
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NICKEL ACETYLACETONATE CATALYZED KNOEVENAGEL CONDENSATIONS AT ROOM TEMPERATURE

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Manojkumar U. Chopade,[a]* Anil U. Chopade[b] and Santosh V. Padghan

Abstract

Nickel acetylacetonate (Ni(acac)2) as a catalyst was tested in Knoevenagel condensation of benzaldehyde with ethyl cyanoacetate in DMSO to provide α-cyano ethyl cinnamate. The substituted benzaldehydes and 3-methylbutyraldehyde gave similar reaction and the corresponding products were obtained in good yields (78-92%) under clean and straightforward condition.

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