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ISSN 2063-5346
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MASS SPECTROMETRIC ANALYSIS PHYTOACTIVE COMPOUNDS AND PHARMACOLOGICAL ACTIVITY MELOCHIA CORCHORIFOLIA

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M.VINOTH, T. CHANDRASEKARAN, A.CHANDRAMOHAN
» doi: 10.48047/ecb/2023.12.si4.409

Abstract

Melochia corchorifolia, a widespread weed found in many tropical and subtropical regions, is a member of the Sterculiaceae family. A medicinal plant called Melochia corchorifolia is used in conventional folk medicine to treat a wide range of medical conditions. Water and methanol extracts of the leaf have been shown in several studies to have antibacterial, antifungal, cytotoxic effects, and anticancer activities.The powdered dry leaves were extracted with ethanol using the Soxhlet equipment. On the ethanolic extract, the phytochemical analysis was performed using conventional methods. Phytoconstituents such phenols, alkaloids, and flavonoids were detected by the analysis. The spectroscopic technique, including GC-MS, have been used to characterize phytoconstituents bioactive molecules.Furthermore, the research was aimed at assessing the Anthelmintic behavior of ethanol extract of Melochia corchorifolia leaves against PheretimaposthumaIndian earthworms, with the result showing that 300 mg/ml proved to be very active by paralyzing and killing the earthworms in a shorter time, followed by Antidiabetic activity in inhibition assay for -amylase activity was evaluated using Melochia corchorifolia leaves showed maximum inhibition of the enzyme with the highest value of 87.10% seen at 100mg/ml.Research findings show that an ethanol extract of the Melochia corchorifolia leaf contains powerful bioactive phytocompounds that might be converted into new Anthelmintic and Antidiabetic properties.

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