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ISSN 2063-5346
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INVESTIGATION OF THE ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF COCCINIA GRANDIS HYDROALCOHOLIC EXTRACT AND IXORA COCCINEA METHANOLIC EXTRACT.

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Dr. Sushil D.Patil1*, Marina G D’souza2, Sarika M.Kamble3, Laxmikanth B. Borse4, ,Amit R.Gaikwad5, Swati G. Talele6, Shankar S.Yelmame7
» doi: 10.31838/ecb/2023.12.si5.037

Abstract

In the current study, methanolic extract of Ixora coccinea leaves and hydro-alcoholic extract of coccinia grandis, both of which are said to have anti-oxidant and anti-bacterial properties, are prepared and analyzed. When compared to the industry standard, the methanolic extract of Ixora coccinea leaves and hydro-alcoholic extract of Coccinia grandis (ICCG) demonstrated significant antibacterial and antioxidant test activities. The inhibition zone diameters were determined to assess the antibacterial activity against Staphylococcus aureus and E. coli using the traditional cup-plate method. In contrast to other formulations, it is clear that ICCG5, which contained clove oil (0.7%), Ixora coccinea (7%), and Coccinia grandis (8%), displayed a greater zone of inhibition. Hence, ICCG5 formulation was found to have better antibacterial and antioxidant activities than other formulations. Results of all other ICCG5 evaluation parameters were all acceptable for all formulations.

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