Nurse-led care coordination is a model of care in which nurses take on the role of coordinating and managing the care of patients, particularly those with complex or chronic conditions. The aim of this review is to examine the existing evidence on the effects of nurse-led care coordination on healthcare utilization and costs, including hospital admissions, emergency department visits, length of stay, and overall healthcare expenditures. By synthesizing the findings from various studies, this review seeks to provide a comprehensive overview of the potential benefits and challenges associated with nurse-led care coordination in healthcare settings. The results of this review suggest that nurse-led care coordination has the potential to reduce healthcare utilization and costs by improving care coordination, enhancing patient outcomes, and promoting more efficient use of healthcare resources. However, the effectiveness of nurse-led care coordination may vary depending on the specific context, population, and healthcare system in which it is implemented. Further research is needed to better understand the mechanisms through which nurse-led care coordination influences healthcare utilization and costs, as well as to identify best practices for implementing and sustaining nurse-led care coordination programs in different healthcare settings.