.

ISSN 2063-5346
For urgent queries please contact : +918130348310

Innovative Research on Garcinia Kola Heckel Seed Extracts Phytochemicals and Related Enzymes Ability to Prevent Important Blood Glucose Levels

Main Article Content

Darla Raju,Devender Kodati 2,Sandeep Kumar Galipelly , Pragati Baghel,Sachinkumar Dnyaneshwar Gunjal,T. Naga Aparna, Satyabrata Jena
» doi: 10.31838/ecb/2023.12.3.091

Abstract

a member of the Guttiferae family of Angiosperms, garcinia kola is the term "bitter kola" is used in trade. Its relevance in folkloric medicine as a purgative, mastcatory, aphrodisiac, etc. is significant. The seed seeds are used in the therapy of a variety of illnesses, including diabetes. Diabetes mellitus is a metabolic illness with several underlying causes characterised by chronic hyperglycemia that can cause serious side effects such neuropathy, nephropathy, retinopathy, and foot ulcers. A screening for qualitative phytochemicals was done. The structure of the isolated chemical was clarified using Gas Chromatography-Mass Spectrophotometry and Fourier Transformed-Infra Red spectroscopy after column chromatographic analysis of the ethyl acetate extract. Under predetermined circumstances, pig pancrease and seed small intestine were used to extract pancreatic -amylase and intestinal glucosidase. The following substances were found: phenolics, flavonoids, cardiac glycosides, alkaloids, coumarins, and phlobatannins. The IC50 values for methanol, ethyl acetate, and n-Hexane preparations were used to block –amylase 0.78 mg/ml, 3.44 mg/ml, 4.89 In contrast, the concentrations of glucosidase were 2.67 mg/ml, 1.68 mg/ml, and 10.29 mg/ml, respectively. from an ethyl solution acetate, the substance ZAAK was obtained. Fourier ZAAK contains an ester and a carboxylic acid, according to transformed-infrared spectra.

Article Details