Hyperglycemic condition can be caused due to impaired insulin secretion or due to resistance to peripheral actions of insulin or due to the presence of both conditions. International Diabetes Federation reported that 415 million adults of age group 20 to 79 were affected with diabetes mellitus in 2015 and the incidence can increase to another 200 million by 2040 and also it was mentioned that the occurrence of one death every six seconds due to diabetes mellitus. The process of inflammation was considered only to benefit the individual to recover from tissue damage and to repair the damaged physiological process. It may lead to the endothelial dysfunction and so it has to be measured and evaluated as an indicator of normal biological, pathogenic or pharmacological responses to a medical intervention. Proper therapeutic approach, risk analysis, and stages of the disease is possible on the early detection of the condition.