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ISSN 2063-5346
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Infants central line-associated bloodstream infection risk influenced by catheter dwell time

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S. Divya, S. Ram Kumar
» doi: 10.31838/ecb/2023.12.sa1.147

Abstract

A central venous catheter is associated with significant morbidity and mortality in the NICU because of the risks of central line-associated bloodstream infections (CLABSI). Study participants were asked to determine whether dwell time affected the incidence of CLABSI. ICR studies retrospectively collected data on 6663 infants with 7783 catheters and 128044 catheter-connected days across 70 neonatal intensive care units. Based on the National Health Surveillance Network definition, CLABSI was developed. The dwell time defined is the number of days between the day of line insertion and the removal of the line or the day of CLABSI. In our analysis, we used a Cox proportional hazards frailty model to estimate survival curves for CLABSI at the end of each week of dwell time. Separate models were generated by line type, controlling Including the effects of facility on postmenstrual age and year, and incorporating postmenstrual age. A median of 29 weeks was found to be the postmenstrual age. Across 500 catheter days, 0.93 cases of CLABSI occurred. CLABSI risk for PICCs was not higher with longer dwell times. There was a significantly higher infection rate in weeks 7 and 9 for tunneled catheters than in week 1. The conclusion of this study is that clinicians should not replace PICCs simply because they are uninfected, but may If tunneled catheters are no longer necessary, remove them before week 7. There is a need for further research to determine what daily maintenance practices, especially for tunneled catheters, may help reduce infection risks.

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