The antioxidant assay results demonstrated that extracts of all plants, including LNS: Leonotis nepetifolia (Stem), BLR: Blumea lacera (Roots), and PASB: Phylanthus acidus (Stem bark), may significantly reduce the amount of free radicals in the body. Their radicals scavenging effects against 2, 2-diphenyl-1-picrylhydrazyl [DPPH], nitric oxide, Super oxide anion, 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulphonate) [ABTS•+], as well as Lipid peroxidation inhibition activities showed dose-dependent activities. It can be revealed that the presence of important bioactive compounds, which are associated with antioxidant activity.