Hydroxylamine and Hydrazine have been extensively investigated and are well known as a mutagenic chemical. Evidence from a number of in vitro and in vivo experiments demonstrating its capacity to generate genetic changes provides strong scientific backing for its labelling as a genotoxic contaminant. In addition, hydroxylamine may be accidentally introduced as a contaminant during the production of a wide range of pharmaceuticals. To guarantee the safety and effectiveness of the finished medicinal product, its presence must be identified and measured. Hydrazine derivatives are used to treat a variety of conditions, including tuberculosis, Parkinson's disease, and cancer. Hydroxylamine derivatives are used to treat tuberculosis and other infectious diseases. Hydrazine and hydroxylamine are also used in the production of a variety of industrial chemicals, including pesticides, herbicides, and polymers. The use of hydroxylamine and hydrazine in drugs has several implications. These chemicals can cause adverse health effects in patients, contaminate the environment, and make it more difficult to control infections. It is important to be aware of the potential risks of these chemicals and to take steps to protect your health.