This study aims to identify problems related to the prescription, dispensing and use of influenza drugs and analgesics in pharmaceutical establishments in Ecuador. A bibliometric analysis was performed to identify the number and type of previous studies related to this topic in the country. A methodology for collecting data in selected pharmaceutical establishments was then developed. The results revealed various problems, such as lack of staff training, inadequate prescribing, over-the-counter dispensing, inappropriate self-medication and lack of adequate information for patients. These problems have a significant impact on the health of the population and require interventions to improve the quality of pharmaceutical care. In conclusion, it is necessary to implement measures that promote the education and training of pharmaceutical personnel, as well as to strengthen the regulation and supervision of the prescription and dispensing of influenza drugs and analgesics.