Acute kidney damage (AKI) is frequent in clinical practice, as a result of an injury or infection sustained before to hospital admission, or it can be acquired in the hospital. AKI is a frequent diagnosis in hospitalized patients, especially in the critically ill and at least occasionally in children who are not critically ill. When patients initially arrive with uremia in clinical practice, it is frequently necessary to accurately diagnose acute or chronic kidney failure, especially in developing nations without a reliable medical record-keeping system. The diagnosis is made simpler if evidence of chronic kidney disease (CKD) is present. Hyaluronic acid may be a biomarker CKD patients